Miscarriages associated with factor V Leiden are more likely to occur later in pregnancy (after the first trimester). Hormones and birth control pills also increase womens risk of blood clots. You may never get a dangerous clot, but its helpful to know the warning signs in case you do. Some people only need treatment for three months, but others will need blood thinner treatment indefinitely. This caution also extends to drug-food interactions. Symptoms of a blood clot depend on what part of your body is affected. Often, those treatments will require hospitalization. Low-salt, low-fat: The plan is already geared toward low-fat and low-salt foods and may be adjusted further if needed. It depends on the specific details of the previous deep vein thrombosis or pulmonary embolism. But some people inherit mutated versions of this gene and develop a condition called factor V Leiden thrombophilia. 0000236831 00000 n Creator and celebrity fitness trainer Harley Pasternak says it's a lifestyle plan, not a diet. The factor V Leiden mutation itself doesnt cause any symptoms. Here's what foods they have in common, and how to build a healthy diet when you have factor V Leiden: Advertisement 1. Most people with factor V Leiden never develop abnormal clots. Nothing beats getting vitamins and minerals from food. It is not a disease. Factor V Leiden is the name of one such blood clotting disorder. Genetic and Rare Disease Information Center. If you are overweight or obese, consider the benefits of losing weight. During long car rides, stop every few hours and take a short walk. Clotting Disorders. If you are heterozygous, theres a 50% chance that your children will get the mutation. Or ask someone to drive you to the nearest emergency room. Just by eliminating junk food, simple carbs, and high-calorie drinks, as in the 5-Factor Diet, most people are likely to see a dip on the scale. Is an uncertain result possible, and what would that mean? Most people have never heard of Factor V Leiden. Want to talk about Multiple Myeloma: Anyone else? Mayo Clinic does not endorse companies or products. 0000001440 00000 n If youve been diagnosed with DVT or a PE, youll have frequent follow-up appointments so your provider can check treatment progress. Be active in ways you enjoy. Anticoagulant Food-Drug Interactions. "Mayo," "Mayo Clinic," "MayoClinic.org," "Mayo Clinic Healthy Living," and the triple-shield Mayo Clinic logo are trademarks of Mayo Foundation for Medical Education and Research. About 1 out of 10,000 people will develop a DVT or PE each year. Having additional genetic blood clotting disorders. If you have factor V Leiden, you inherited either one copy or, rarely, two copies of the defective gene. How does prothrombin gene mutation affect my body? When enough fibrin has been made, a substance called activated protein C (APC) inactivates factor V, helping stop the clot from growing any larger than necessary. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2018. By continuing to browse this site you agree to our use of cookies. The Factor V Leiden protein is harder to turn off than the normal Factor V protein. Advertising revenue supports our not-for-profit mission. Factor V and other proteins work together to help your blood clot when necessary. Why? 0000006722 00000 n Green tea in high amounts could reduce PT-INR values. News-Medical. Inherited thrombophilias in pregnancy. Cleveland Clinic is a non-profit academic medical center. This change causes it to resist other proteins that stop excessive clotting. This is your bodys reaction to an injury that prevents you from bleeding too much. Advertising revenue supports our not-for-profit mission. 3. Cranberry products are not significant unless taken in high amounts, as for urinary infections. Should people with Factor V Leiden avoid Vitamin K? Avoid smoking, vaping and tobacco use. Usually, once the clot is formed, factor V is "turned off," but not in those with factor V Leiden. If signs and symptoms do occur, they can include: Known as a pulmonary embolism, this occurs when a portion of a DVT breaks free and travels through the right side of your heart to your lung, where it blocks blood flow. This mutation can increase your chance of developing abnormal blood clots, most commonly in your legs or lungs. People who have inherited factor V Leiden from only one parent have a 5 percent chance of developing an abnormal blood clot by age 65. If you notice any of these problems, call your doctor right away. Bauer KA. Complex carbohydrates (vegetables, sweet potato, wild rice, beans, lentils, oatmeal, quinoa). When anticoagulants are prescribed, a prothrombin time (PT) test is used to evaluate its effectiveness. It is important to discuss potential interactions between existing and new medications to prevent or recognize any side effects. It is recommended that patients on anticoagulants drink two or fewer alcoholic drinks per day. These include: Talk to your healthcare provider about your risk of developing blood clots and what precautions you should take. Study Results Demonstrate VTE Treatment Satisfaction Among Patients, Managing Anticoagulants Before, During, and After Medical Procedures, Helping Women Make Choices About Contraception Following DVT Blood Clots, Panel Discussion: Blood Clots & Womens Health, Frequently Asked Questions: COVID-19 and Blood Clotting, Stop the Clot, Spread the Word Hospitalization, Toolkit for Knee and Hip Replacement Patients, Health Disparities and the VTE Mississippi Initiative, Atrial Fibrillation (AFib) and Clot-Provoked Stroke, Questions to Ask Your Doctor After Having a Blood Clot, NBCA Atrial Fibrillation Awareness Survey, Impact of Blood Clots in the Black Community Research Opportunities, NBCA Sports & Wellness Institute: Team Stop the Clot, Council of Emerging Researchers in Thrombosis (CERT), Medical & Scientific Advisory Board (MASAB), not enough clotting power leads to bleeding problems, too much clotting power can lead to the formation of dangerous blood clots. The exercise portion of the program might have to be changed if you are trying to follow the exercise guidelines of the American Heart Association. This can be a life-threatening situation. A DVT may not cause any symptoms. Nelson JG. Carbohydrates with lower glycemic index (GI) values raise blood sugar levels less than foods with a higher GI, but their use in weight loss has not been as well studied. If you have an inactive (sedentary) lifestyle, consider how you could gradually increase your physical activity at home, school, work or play. Accessed June 4, 2018. "Anticoagulant Food-Drug Interactions". These blood clots can be life-threatening. The factor V Leiden mutation itself doesnt have any specific treatment. For factor V Leiden, some basic questions to ask your doctor include: If your doctor recommends genetic testing, some questions you might want to ask the genetic specialist include: Connect with others like you for support and answers to your questions in the Blood Cancers & Disorders support group on Mayo Clinic Connect, a patient community. Get useful, helpful and relevant health + wellness information. 0000001914 00000 n Symptoms may resolve within days or months, depending on the location and severity of your deep vein thrombosis or pulmonary embolism. In most people, a protein called activated protein C regulates the activity of . 0 endstream endobj 77 0 obj<> endobj 79 0 obj<>/Font<>>>/DA(/Helv 0 Tf 0 g )>> endobj 80 0 obj<> endobj 81 0 obj<>/Font<>/XObject<>/ProcSet[/PDF/Text/ImageC]/ExtGState<>>> endobj 82 0 obj<> endobj 83 0 obj<> endobj 84 0 obj<> endobj 85 0 obj<> endobj 86 0 obj<> endobj 87 0 obj[/ICCBased 102 0 R] endobj 88 0 obj<> endobj 89 0 obj<> endobj 90 0 obj<>stream But you will have to be very organized and motivated to stay on track. There are many foods that can be beneficial to the health of patients with Factor V Leiden. But in people who do, these abnormal clots can lead to long-term health problems or become life-threatening. Going on a long flight or a very long road trip. Pasternak promises that eating a balanced meal five times a day will keep your blood sugar low and stable. 0000001706 00000 n At least 1 of the genes that you inherited is the mutated gene that makes the Factor V Leiden protein. What about my children?. In addition, this mutation only increases the risk of vein clots (deep vein thrombosis or pulmonary embolism). On the other hand, chronic alcohol consumption reduces the INR. Anticoagulants, commonly called blood thinners, are a group of medications that impede the blood clotting process. Mayo Clinic on Incontinence - Mayo Clinic Press, NEW The Essential Diabetes Book - Mayo Clinic Press, NEW Ending the Opioid Crisis - Mayo Clinic Press, FREE Mayo Clinic Diet Assessment - Mayo Clinic Press, Mayo Clinic Health Letter - FREE book - Mayo Clinic Press, Mayo Clinic Graduate School of Biomedical Sciences, Mayo Clinic School of Continuous Professional Development, Mayo Clinic School of Graduate Medical Education, Book: Mayo Clinic Family Health Book, 5th Edition, Newsletter: Mayo Clinic Health Letter Digital Edition. 1-ranked heart program in the United States. As such, daily intake or extra supplementation with vitamin K is typically unnecessary to keep body stores at healthy levels. Chan School of Public Health. 1-ranked heart program in the United States. Others can be life-threatening. 0000003553 00000 n Your provider may think you have a clotting problem if you: There is no specific treatment for the mutation itself. Lean protein: Prioritize lean proteins such as chicken, turkey and lean beef. Your skin may also feel warm to the touch or look red or discolored. . If you have never had a blood clot, you do not need treatment with blood thinners. Factor V Leiden is the most common inherited condition that causes an increase in blood clotting. Still, there is research that suggests that a diet of low GI foods is more likely to cause weight loss, at least in the short term. Exercise regularly, such as walking, swimming or riding a bike 3 times a week. They are used to treat conditions such as embolic ischemic stroke, deep vein thrombosis, and pulmonary embolism. New York, N.Y.: McGraw-Hill Education; 2016. https://accessmedicine.mhmedical.com. In this interview, we speak to Ceri Wiggins, a Director at AstraZeneca, about the many applications of CRISPR and its role in discovering new COPD therapies. HW}Wc)h"Y$ x N,@I)T7;&?/s"C0]=wSb;{PlYdA&Trb"agbH0Hok8bio@k'q Do I need to take medication to prevent additional blood clots? If you or a loved one have factor V Leiden, you might feel scared about what the future will bring. If youve had a deep vein thrombosis or pulmonary embolism before and know you have the prothrombin gene mutation, you may need a prescription for low-dose (preventive doses) of an injectable blood thinner (such as heparin or a low-molecular-weight heparin) during your pregnancy and for a few weeks after delivery. Youll spend roughly the same amount on groceries if you keep the bulk of your protein purchases to eggs, lean meats and poultry, and fat-free dairy, as opposed to seafood. You must do the 25-minute 5-Factor workout five days a week. Your brothers and sisters may have inherited the mutated gene for Factor V Leiden, just like you did. Connect with others like you for support and answers to your questions in the Blood Cancers & Disorders support group on Mayo Clinic Connect, a patient community. Mayo Clinic, Rochester, Minn. June 17, 2018. Build physical activity into your daily life. The two most common hematological diseases the impairment of Factor V causes are Factor V deficiency or Owren's disease, and Factor V Leiden. Since then I was also diagnosed w My name is MARTIN R. LEMIEUX, and for over 20 years now Ive survived five DVTS BLOOD CLOTS in my left leg, one clot in my right leg, and another clot in my left pelvic area. In heterozygous carriers of this mutation, the risk of developing a deep vein thrombosis or pulmonary embolism is about two to three in 1,000. Do you recommend genetic testing for any of my family members? advice, care, or treatment. Your doctor can tell you how much fluid is right for your age, health and activity level. The factor V Leiden mutation does not itself cause any symptoms. Your healthcare provider may suspect you have factor V Leiden if you have a history of venous thromboembolism. Factor V Deficiency Vs. Owned and operated by AZoNetwork, 2000-2023. Tenderness or pain in your leg or arm, which you may only feel when standing or moving around. Factor V Leiden G1691A and Prothrombin Gene G20210A Mutations on Pregnancy Outcome. With Factor V Leiden the risk of a blood clot increases with age 0 100 200 300 400 500 600 700 800 900 1000 Risk per 100,000 people Childhood 20's 40's 80's Having 1 Factor V Leiden gene (heterozygous type) slightly increases the chance of developing a blood clot. In: Williams Hematology. A cough that produces bloody or blood-streaked sputum. If youcannot reach your doctor, go to the nearest hospital emergency room. Factor V is a protein or clotting factor that helps create the enzyme reactions that form the fibrin in the clot. A lot of people carry the genetic mutation and a few people develop blood clots that are related to Factor V Leiden. If you want to increase the amount you're eating, your doctor can help you make the adjustment slowly, with appropriate adjustments to your medication. The mutation in itself is not a reason to avoid donating blood, but you should not give blood if you are using an anticoagulant (blood thinner). Clots can form in the veins near your bones that carry a lot of blood (deep veins), a condition called deep vein thrombosis. At this time, we cant treat or change our genes. It even tells you what staples to keep on hand so you will always be able to get a quick meal together. They were hot, red, and huge. Here's what foods they have in common, and how to build a healthy diet when you have factor V Leiden: 1. Barbara Woodward Lips Patient Education Center. Clots can form in the veins near your bones that carry a lot of blood (deep veins), a condition called deep vein thrombosis. 0000003332 00000 n Accessed June 4, 2018. Both men and women can have factor V Leiden. But theres no clear consensus, and researchers continue to explore what risks, if any, factor V Leiden poses during pregnancy. on this website is designed to support, not to replace the relationship Your F5 gene controls the production of a protein called factor V, which helps your blood clot when needed (such as after an injury). Lockwood CJ, et al. But if you do, prompt treatment can manage your condition. If you have the prothrombin gene mutation but never had a deep vein thrombosis or pulmonary embolism before, you will not need a blood thinner during or after pregnancy. This disorder may raise your risk of a miscarriage or other complications. Yes, you may be able to donate blood if youre not taking a blood thinner. Mayo Clinic is a not-for-profit organization. (On the contrary, these are all heart-healthy foods.). Signs and symptoms may include: Seek medical attention immediately if you have signs or symptoms of either a DVT or a pulmonary embolism. If you cant walk around, flex your ankles and point your toes up and down. Because factor V Leiden is a blood clotting condition, you need to have a discussion with your health care team about your dietary restrictions if you are on a blood-thinning medication like warfarin. Factor V is a protein that is needed for blood to clot properly. You may be treated with blood thinners until the risk has passed. National Heart, Lung, and Blood Institute. As a result, your blood may clot more easily than it should, leading to serious complications. "Anticoagulant Food-Drug Interactions". This is why Factor V Leiden is sometimes called Activated Protein C Resistance and why people with this mutation clot more than those without it. The prothrombin gene mutation can make you more likely to get harmful blood clots, but you may never get one. If you have factor V Leiden, you may have many questions. A food-drug interaction is when a particular food or drink affects the way in which a certain medication works. Please use one of the following formats to cite this article in your essay, paper or report: Zoppi, Lois. Together we can #stoptheclot! Most notably, you will need to be aware of your vitamin K consumption. 0000003776 00000 n As a result, clotting goes on longer than usual. If you get the mutation from both of your parents, you are homozygous (you have two abnormal copies of the Factor II gene). Doctors generally prescribe blood-thinning medications to treat people who develop abnormal blood clots. 6. Where's the Beef? 0000007946 00000 n Read below where Experts have answered questions about Factor V Leiden. Because its an inherited condition, you cant prevent the prothrombin gene mutation. I was placed on maternity leave and put on bed rest. In the spring of 2010, I was working and felt that it was a little difficult to bend my right knee / walk - I felt very little swelling / heat so I thought little of it, especially in light of a prior history of having knee problems in that same leg. Information on diseasemaps.org is reported by users and is not medical advice. Do I need to limit my activity in any way? xref No, you cant prevent this blood clotting disorder. You will most likely not have a dangerous blood clot, but your provider can provide counseling on how to reduce the risk of a deep vein thrombosis or pulmonary embolism. Toll Free: 877.4.NO CLOT, National Blood Clot Alliance Enjoy a variety of foods from the 4 food groups. The condition it self does not require a special diet. 3. One or both of the factor V genes can be mutated and cause the altered form of the factor V protein known as the Factor V Leiden protein to be made. The best diet to follow is one full of foods that support heart health, because these are also naturally good for your blood health. This gene carries instructions that tell your body how to properly create the factor V protein. Calorie counting is not a feature of this diet plan. Thank you to @angiodynamics one of our corporate sponsors for the 100,000 Reasons Challenge for their support during #BCAM2023. Factor V Leiden This results from a genetic change that increases the risk of blood clots, especially in deep veins. Your provider will advise you on whether you need testing, as well as on the pros and cons of testing. You have 1 Factor V Leiden gene from one parent and 1 normal Factor V gene from your other parent. These medications (called anticoagulants) help to prevent clotting. Alcohol interacts with a large number of medications. In situations where there is a greater chance of clotting (such as surgery, a leg cast, a serious illness or pregnancy) you may be treated with blood thinners until the risk has passed. Symptoms of a deep vein thrombosis or pulmonary embolism typically start getting better soon after specific treatment is started. Factor V Leiden. That risk is several times higher in homozygous carriers. For those who are watching their cholesterol, there have been some studies that show low GI diets are helpful at lowering cholesterol levels. Venous thromboembolism. Healthy fats: Eat healthy fats each day such as olive oil, nuts, seeds and avocado. Youre at risk for having factor V Leiden if one of your parents carries a copy of the mutated F5 gene. Any use of this site constitutes your agreement to the Terms and Conditions and Privacy Policy linked below. She maintains a focus on anxiety disorders and depression and aims to explore other areas of mental health including dissociative disorders such as maladaptive daydreaming. We do not endorse non-Cleveland Clinic products or services. Factor V Leiden is an inherited blood clotting disorder that raises your risk of deep vein thrombosis or a pulmonary embolism. National Heart, Lung, and Blood Institute. What will a positive or negative result tell me? Deficiencies of antithrombin and proteins C/S, elevated fibrinogen levels, and other clotting disorders also raise risk. Factor V Leiden and prothrombin gene mutations cause about 50% of inherited coagulopathies. Having 2 Factor V Leiden genes (homozygous type) makes the risk much greater . However, the disorder raises your risk compared to people without the disorder. But its important that these individuals discuss with their doctors what they should be aware of and what they can do to minimize the risk of DVT or PE. Here are a few to help you start the conversation: Factor V is a coagulation factor, or protein, in your blood. A. INR values of between 2.0 and 3.0 are considered effective therapeutic values while on anticoagulant therapy. Some hospitals do only the DNA test and not the screening test. Factor V Leiden is the most common one. News-Medical.Net provides this medical information service in accordance Keep going to your follow-up appointments with your provider, especially if youre taking a blood thinner. 0000237253 00000 n This site complies with the HONcode standard for trustworthy health information: verify here. Individuals who happen to know that they have factor V Leiden but have never had blood clots dont have to be prescribed any blood thinners. Or maybe youve had no issues, but your loved one needed treatment for DVT. It is generally advised that patients taking anticoagulants keep to a balanced and consistent diet balanced throughout their treatment course to avoid fluctuations in treatment efficacy. National Library of Medicines list Before using birth control pills or hormone therapy for menopause. 2. 4. News-Medical. Both of those types of injectable blood thinners are safe for your baby. Kaushansky K, et al., eds. This site complies with the HONcode standard for trustworthy health information: verify here. Fiber (whole-grain cereal, beans, wild rice, flourless wheat bread. According to NutritionData, the best sources of folate per 100 g serving are: Beans and lentils (~50% RDI) Raw spinach (49% RDI) Asparagus (37% RDI) Romaine (Cos) lettuce (34% RDI) Broccoli (27% RDI) Avocado (20% RDI) Oranges/Mangoes (~10% RDI) If you have Factor V Leiden, you have a greater chance of developing blood clots. But the plan would have to be modified to make it appropriate if you have these or other conditions. You should not rely on the information provided as a substitute for actual professional medical Did I get the mutation from both parents or just one? High-Protein Diets -- Do They Really Work? An INR value of 1.1 or below is considered normal in healthy patients, with lower values indicating faster clotting, while higher values show slower clotting rate. Keywords: papillophlebitis, factor v leiden, methylenetetrahydrofolate reductase mutation, retinal venous disease Introduction Papillophlebitis is a rare disease (higher prevalence in women of 20-35 years old), characterized by optic disc edema, retinal venous engorgement, and retinal hemorrhages, mainly located within the peripapillary area . For children with one affected gene, the chance of getting a blood clot increases 10 times. Where's the Health Benefit? The following supplements are theoretically capable of inhibiting VKAs, but their clinical effect is insignificant: Studies have shown that there is a 58% higher likelihood of achieving PT-INR values in the optimal therapeutic range of 2.0 to 3.0 if patients on VKA medication avoid herbal supplements or take them three or fewer times a week. .wpcdt-timer-24806 {background-color: #aaaaaa;}.wpcdt-timer-24806 .wpcdt-title, .wpcdt-timer-24806 .wpcdt-desc, .wpcdt-timer-24806 .wpcdt-desc p{color: #b81d32;}.wpcdt-timer-24806 .wpcdt-clock-circle h4, Factor V is a helper in the enzyme reactions that form the fibrin in the clot. Rochester, Minn.: Mayo Foundation for Medical Education and Research; 2018. between patient and physician/doctor and the medical advice they may provide. 1, 2 This Cardiology Patient Page will describe deficiencies in the natural anticoagulants, protein C, protein S, and antithrombin that may result in either There are 2 copies for Factor V gene, which are passed down from our parents. 2. Camomile in large quantities, a herbal treatment that is used to treat anxiety, catarrh and gastric problems, has also been implicated in a case of severe bleeding in a 70-year-old woman. In 2010 I was pregnant with my son. Will Eating More Protein Help Your Body Gain Muscle Faster? Accessed June 4, 2018. If you have symptoms of a pulmonary embolism, you should go to the closest emergency room. Factor V Leiden (FAK-tur five LIDE-n) is a mutation of one of the clotting factors in the blood. Zoppi, Lois. Smart Grocery Shopping When You Have Diabetes, Surprising Things You Didn't Know About Dogs and Cats, Smoking Pot Every Day Linked to Heart Risks, Artificial Sweetener Linked to Heart Risks, FDA Authorizes First At-Home Test for COVID and Flu, New Book: Take Control of Your Heart Disease Risk, MINOCA: The Heart Attack You Didnt See Coming, Health News and Information, Delivered to Your Inbox. Philadelphia, PA 19182-5687. There currently arent any genetic treatments that can stop someone from inheriting a mutated F5 gene. The liver is responsible for breaking down alcohol and some medications, and this may cause a slower than normal metabolism of the anticoagulant, increasing the drug concentration in the blood, and hence the risk of bleeding. There is no specific "diet" for people with factor V Leiden, but there are foods that can help keep your blood and body healthy, which may reduce your risk of developing a blood clot. Inherited thrombophilias in pregnancy. Everyone is born with two copies of the factor V pronounced factor five gene. Phone: 703.935.8845 Drink plenty of fluids (without alcohol). All rights reserved. You may not need to do anything other than lead a healthy lifestyle to minimize the risk of a deep vein thrombosis or pulmonary embolism. Talk to your healthcare provider to receive advice tailored to your needs. If you have the homozygous type, your child will inherit a Factor V Leiden gene. Foods high in saturated fat, including animal and dairy fat, coconut oil, palm oil and processed meat. All rights reserved. This gene is responsible for aiding in normal blood clotting. They are prescribed to avoid the development of harmful blood clots. With Factor V Leiden the risk of a blood clot increases with age 0 100 200 300 400 500 600 700 800 900 1000 Risk per 100,000 people Childhood 20's 40's 80's Having 1 Factor V Leiden gene (heterozygous type) slightly increases the chance of developing a blood clot. https://www.uptodate.com/contents/search. Talk to your doctor about your fitness goals before starting this program. You inherited one Factor V Leiden gene from your mother and one from your father. More info. In rare cases, you may need a catheter procedure or surgery to remove the bulk of the clots. Added sugars in excess of 24 grams per day for people assigned female at birth and 32 grams per day for people assigned male at birth, per the American Heart Association. This content does not have an Arabic version. What can I do to support a healthy pregnancy? The prevalence of factor V Leiden varies by ethnicity. Effective measures to eliminate or reduce other risk factors for DVT or PE, such as smoking cessation, weight loss and having a more active lifestyle. Eat well. If you have other chronic conditions such as diabetes, work with your health team to manage your health. Fruits and vegetables: Get at least five servings of fruits and veggies throughout the day, and incorporate all different kinds. Each part of the plan revolves around the number five. Counseling prior to taking birth control pills or before becoming pregnant. If you know you have the factor V gene mutation, you can work to make your body an inhospitable place for clots, starting with something under your control: your diet. However, it is often advised to avoid foods high in Vitamin K. Below is a list of foods that should be avoided because of their . Before becoming pregnant, talk with your doctor about how your risk of blood clots can be managed during pregnancy, childbirth and for 6 weeks postpartum. Healthy fat (from fish such as salmon, tuna, mackerel, sardines, rainbow trout, or peanut oil, olive oil, canola oil, sunflower oil, Sugar-free drinks (water, sugar-free soda, coffee, tea, or an unsweetened energy drink). Factor V that becomes impaired can cause numerous issues with the health of the human blood. Limitations: You can eat anything you want on your weekly cheat day." When the bleeding stops, different proteins tell the clotting factors to break apart so the clot can dissipate. These proteins are essential helpers that support hemostasis. Most people with factor V Leiden never develop abnormal clots. Take your questions to your healthcare provider and get the answers you need. 2005 - 2023 WebMD LLC. However, your doctor might suggest that you take extra precautions to prevent blood clots if you have the factor V Leiden mutation and are going to have surgery. Vitamin K is necessary for making the proteins that aid in blood clotting, according to the Harvard T.H.
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